New! CWW systematic review of global soil-transmitted helminthiasis prevalence and intensity studies
CWW is pleased to share a systematic literature review1 titled, “Qualitative systematic literature review of global soil-transmitted helminthiasis prevalence and intensity studies.” The literature review was undertaken to assess the availability and quality of STH data starting from 2006, when several STH endemic countries began implementing mass drug administration for STH control.
The literature review included 209 studies published between 2006 and 2018 that fit the inclusion criteria. Findings from the literature review indicated that the available STH epidemiological data are “fragmented, mostly of questionable quality, and minimally useful for regional or global program decisions.” The authors recommend a standardized approach to gathering STH program data, based on a comprehensive global monitoring and evaluation framework that will allow for pooling of information across countries and regions to guide global policy and progress.
1Diaz, Michael R., et al. (2020) Qualitative systematic literature review of global soil-transmitted helminthiasis prevalence and intensity studies.
Post-intervention epidemiology of STH in Bangladesh: Data to sustain the gains
Dhakal, S., Karim, M.J., Kawsar, A.A., Irish, J., Rahman, M., Tupps, C., Kabir, A., Imtiaz, R. (2020). Post-intervention epidemiology of STH in Bangladesh: Data to sustain the gains. PLOS Neglected Tropical Diseases 14(12): e0008597. https://doi.org/10.1371/journal.pntd.0008597
Qualitative systematic literature review of global soil-transmitted helminthiasis prevalence and intensity studies
STH prevalence and intensity measures form the basis of WHO goals and action thresholds for national programs in endemic countries. Considering the importance of these STH burden measures, we conducted a published literature review from 2006 (start of drug donations) through 2018 to study the quality and distribution of evidence. We grouped the resulting studies according to their possible utility and application towards tracking the WHO and national program progress. Results confirmed the paucity and diversity of study methods, challenging generalization across regions or even countries, and lost efficiency of sparse research resources in this area. We conclude by suggesting standardized approaches to guide research that is closely linked to program actions and can guide global policy and progress.
First international external quality assessment scheme of nucleic acid amplification tests for the detection of Schistosoma and soil-transmitted helminths, including Strongyloides: A pilot study
Cools P, van Lieshout L, Koelewijn R, Addiss D, Ajjampur SSR, et al. (2020) First international external quality assessment scheme of nucleic acid amplification tests for the detection of Schistosoma and soil-transmitted helminths, including Strongyloides: A pilot study. PLOS Neglected Tropical Diseases 14(6): e0008231. https://doi.org/10.1371/journal.pntd.0008231
COVID-19 in the least developed, fragile, and conflict-affected countries — How can the most vulnerable be protected?
Ebrahim, S. H., Gozzer, E., Ahmed, Y., Imtiaz, R., Ditekemena, J., Rahman, N. M. M., Schlagenhauf, P., Alqahtani, S. A., & Memish, Z. A. (2021). COVID-19 in the least developed, fragile, and conflict-affected countries—How can the most vulnerable be protected? International Journal of Infectious Diseases, 102, 381–388. https://doi.org/10.1016/j.ijid.2020.10.055
Children Without Worms (CWW) hosts the Neglected Tropical Diseases (NTD) Supply Chain Forum (SCF) meeting
CWW hosted the second of the bi-annual meetings of the NTD SCF in September 2020. Participants included representatives from national Ministries of Health, the WHO, implementing partner organizations, and pharmaceutical donors such as Merck Healthcare KGaA, Merck Sharp & Dohme Corp., J&J, GSK, Eisai, and Pfizer. (Access meeting report here.)
Spread over the course of three days via a virtual platform, the meeting included updates from representatives of pharmaceutical donors and the various working groups set up to solve supply chain management challenges in delivering pharmaceutical products to endemic countries.
The supply chain forum was particularly relevant this year, as CWW encouraged dialogue and creative solutions to COVID-19 challenges. Participants identified that with the reduction of flights, border closures and restrictions, the delivery of NTD medications has posed many challenges. Further, mass drug administrations (MDA) have decreased because of COVID-19 restrictions such as school closures. Participants noted that missed MDAs may also trigger the need for an additional MDA in 2021 to keep the programs on track.
To overcome such challenges, NTD SCF participants proposed concise measures for ensuring the delivery of medicines to affected communities. Several recommendations were made at the end of the three-day meeting, including next steps to guide the future of the NTD SCF.
The next virtual forum meeting is scheduled for February 23-24, 2021.
CWW has been working with the Ministry of Health, Bangladesh and other partners to strengthen national NTD program monitoring and data management through use of the Integrated Community-Based Survey for Program Monitoring (ICSPM). Click through the slideshow below to learn more about ICSPM in Bangladesh and our collaborative progress towards elimination of STH as a public health problem among children.
CWW is hosting the annual STH Advisory Committee meeting October 28-29, 2020.
Purpose of the meeting: The purpose of the annual STH Advisory Committee meeting is to discuss new research and evaluate current gaps in achieving WHO STH goals to provide relevant technical and scientific advice on STH control.